Sonic Hedgehog Protein (SHH) (AA 25-198, C25I)
Aperçu rapide pour Sonic Hedgehog Protein (SHH) (AA 25-198, C25I) (ABIN2816989)
Antigène
Voir toutes Sonic Hedgehog (SHH) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 25-198, C25I
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Séquence
- Cys25 - Gly198 (Cys25Ile-Ile), with an N-terminal Met, Accession # Q62226
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Attributs du produit
- Biological Activity: The ED50, as determined by inducing alkaline phosphatase production using murine C3H10T1/2 cells, is less than 300 ng/mL.
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Stérilité
- 0.2 μm filtered
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Sonic Hedgehog (SHH) (AA 25-198), (Cys25IleIle-Mutant) (Active) protein
SHH Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Sonic Hedgehog (SHH) (AA 24-197), (Cys24IleIle-Mutant) (Active) proteinSHH Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Sonic Hedgehog (SHH) protein (His tag)SHH Origine: Souris Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Sonic Hedgehog (SHH) (Active) proteinSHH Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
Sonic Hedgehog (SHH) (AA 181-280) protein (GST tag)SHH Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Sonic Hedgehog (SHH) protein (His tag)SHH Origine: Humain Hôte: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Sonic Hedgehog (SHH) (Active) protein (His tag)SHH Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Sonic Hedgehog (SHH) (AA 25-198) protein (His tag)SHH Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE SDS
Sonic Hedgehog (SHH) proteinSHH Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant 97,00% SDS
Sonic Hedgehog (SHH) (AA 24-197) protein (His tag)SHH Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 20 mM PB, pH 7.4, 150 mM NaCl
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Stock
- -20 °C
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- Sonic Hedgehog (SHH)
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Autre désignation
- Shh
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Sujet
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Relevance: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO. {ECO:0000269|PubMed:14687547, ECO:0000269|PubMed:7736596}.
Synonyms: SHH, , Sonic hedgehog protein C-product Sonic hedgehog protein 27 kDa product,], -
Poids moléculaire
- 19.9 kDa
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UniProt
- Q62226
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Pathways
- Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Antigène
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